Genetic variation in mouse salivary amylase rate of synthesis
- 1 August 1979
- journal article
- research article
- Published by Springer Nature in Biochemical Genetics
- Vol. 17 (7-8) , 665-682
- https://doi.org/10.1007/bf00502125
Abstract
Heterozygotes from matings of the mouse strains YBR/Cv and C3H/As have about 3 times more YBR-amylase than C3H-amylase in the saliva. The determinant for this quantitative effect is located on linkage group XVI close to or within the structural gene for salivary amylase. The quantitative effect is the result of an increase in the rate of synthesis of YBR-amylase, and the determinant is cis acting. Studies of other mouse strains suggest that regulatory genetic elements may modulate salivary amylase production.Keywords
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