The Spectrophotometric Determination of Thalidomide in Body Fluids
- 1 December 1961
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 13 (Supplement) , 117T-121T
- https://doi.org/10.1111/j.2042-7158.1961.tb10501.x
Abstract
An ultra-violet spectrophotometric method is described for the determination of thalidomide in blood, plasma or urine. Thalidomide is extracted from the sample with chloroform, and the drop in extinction measured when solutions are treated with alkali. The method has been used to determine the amount of drug present in animal and human blood.Keywords
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