A prospective study of predictive factors of ovarian response in 'standard' IVF/ICSI patients treated with recombinant FSH. A suggestion for a recombinant FSH dosage normogram
Open Access
- 1 April 2003
- journal article
- research article
- Published by Oxford University Press (OUP) in Human Reproduction
- Vol. 18 (4) , 781-787
- https://doi.org/10.1093/humrep/deg181
Abstract
BACKGROUND: The aim was to identify independent predictors of ovarian response to recombinant (r)FSH through a multiple regression analysis. METHODS: Prospective study including 145 ‘standard’ patients treated with 150 IU/day of rFSH during their first IVF/ICSI cycle. Down‐regulation was achieved with long agonist protocol. The following were examined as possible predictive factors: age, body mass index, cycle length, smoking status and on day 2–5: total ovarian volume, total number of antral follicles (P < 0.001) and the number of oocytes (P < 0.001). CONCLUSIONS: Among 12 investigated possible predictive factors in ‘standard’ patients, the total number of antral follicles and ovarian stromal blood flow assessed by total Power Doppler score are the two most significant predictors of ovarian response. Suggestion for an rFSH dosage normogram is presented.Keywords
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