Episodic Complete Airway Obstruction in Infants

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Abstract
Four [human] infants with episodic silent complete obstructed apnea are described. All had central sleep apnea, 3 had hypoventilation and none had obstructive apnea observed on polygraphic recordings. Two infants were siblings of a sudden infant death syndrome victim and 1 was a sibling of a near miss infant. One infant died as a result of a prolonged episode that began while she was awake. In 2 infants apnea was controlled with theophylline administration, and in the 3rd infant resolution of the episode was temporally related to atropine administration.

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