Replacement of Margarine on Bread by Rapeseed and Olive Oils: Effects on Plasma Fatty Acid Composition and Serum Cholesterol

Abstract
The effects of zero erucic acid rapeseed oil and olive oil on plasma fatty acid composition and serum cholesterol were studied in margarine users (n = 46). The replacement of margarine on bread by these oils accounted, on average, for 16 % of the total fat and 7% of the total energy intake. Fatty acid analysis of total plasma indicated a dose-dependent rise in α-linolenic (α-LLA) and oleic acid (OA) levels during rapeseed and olive oil substitutions, respectively. Rapeseed oil substitution increased the proportion of eicosapentaenoic acid (0.4 %-units, on average) in plasma phospholipids. A slight decrease in low-density lipoprotein cholesterol (LDL-C) and an increase in high-density lipoprotein cholesterol (HDL-C, 4.5%, p

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