Synthesis of trans-2,6-dialkylpiperidines by 1,3-cycloaddition of alkenes to 2-alkyl-2,3,4,5-tetrahydropyridine oxides
- 1 January 1986
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 16,p. 1287-1288
- https://doi.org/10.1039/c39860001287
Abstract
A convenient route to trans-2,6-dialkylpiperidines by cycloaddition of alkenes to 2-alkyl-2,3,4,5-tetrahydropyridine oxides followed by reductive cleavage of the resulting isoxazolidine is illustrated by a synthesis of the fire ant-venom alkaloid, solenopsin.Keywords
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