Hydroxy-Methylglutaryl–Coenzyme A Reductase Inhibition Promotes Endothelial Nitric Oxide Synthase Activation Through a Decrease in Caveolin Abundance
- 2 January 2001
- journal article
- other
- Published by Wolters Kluwer Health in Circulation
- Vol. 103 (1) , 113-118
- https://doi.org/10.1161/01.cir.103.1.113
Abstract
Background—Hypercholesterolemia is causally associated with defects of endothelial nitric oxide (NO)–dependent vasodilation. Increased uptake of cholesterol by endothelial cells (ECs) upregulates t...Keywords
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