Implementation of macrocycle conjugated antibodies for tumour-targetting
- 1 January 1989
- journal article
- research article
- Published by Walter de Gruyter GmbH in Pure and Applied Chemistry
- Vol. 61 (9) , 1637-1641
- https://doi.org/10.1351/pac198961091637
Abstract
Monoclonal antibodies may be selectively functionalised with macrocyclic ligands, permitting the transport of an imaging or cytotoxic metal radionuclide specifically to a tumour. Antibodies conjugated to [13] and [14]-membered tetraazamacrocycles allow 64Cu or 67Cu labelled antibody to be used for imaging or therapy.This publication has 4 references indexed in Scilit:
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