Dose Effect of Clopidogrel Reloading in Patients Already on 75-mg Maintenance Dose
Open Access
- 16 September 2008
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation
- Vol. 118 (12) , 1225-1233
- https://doi.org/10.1161/circulationaha.108.776757
Abstract
Background— Clopidogrel loading has mostly been studied in clopidogrel-naïve patients. Whether clopidogrel-treated patients readmitted for an acute coronary syndrome or percutaneous coronary intervention can benefit from a new load of clopidogrel and at what dose remain unknown. Our aim was to evaluate the impact of 3 different strategies of administration of a loading dose of 900 mg clopidogrel in patients already treated with a maintenance dose of 75 mg clopidogrel for at least 7 days on residual platelet aggregation.Keywords
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