The polarographic determination of chlorpromazine and chlorpromazine sulphoxide

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Abstract
Cathodic polarography of solutions containing between 0·1 and 5·0 μg/ml of both chlorpromazine and its sulphoxide enables the sulphoxide to be determined directly. Reductive polarography of the solution after bromination gives an additive wave from which the chlorpromazine is determined by subtraction. The method has been applied to urine, interfering substances being removed by ion-exchange on Amberlite resins.