Cyclisation reactions. Part III. Cyclisation of trans-2,3-epoxy-9-m-methoxyphenyl-2,6-dimethylnon-6-ene

Abstract
9-m-Methoxyphenyl-2,6-dimethylnona-2,6-diene (VI) has been converted into the 2,3-epoxide (VIII) and the latter cyclised to give (±)-13-methoxypodocarpa-8,11,13-trien-3β-ol (IX)(25%) as the major product. An alcohol and a ketone isolated in 12 and 17% yield respectively have been tentatively assigned as the 11-methoxy-isomer (X) and trans-3-(2-m-methoxyphenylethyl)-2,2,4-trimethylcyclohexanone (XII).

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