TISSUE DISTRIBUTION OF BOVINE I-125-SUPEROXIDE DISMUTASE IN MICE
- 1 January 1976
- journal article
- research article
- Vol. 15 (4) , 641-654
Abstract
I.v. injected 125I-bovine superoxide dismutase in mice is essentially cleared from organs in 24 h. The 125I activity per gram of tissue at 1 h varies among organs with the brain and kidneys showing the lowest and highest levels, respectively. Within tissues, degradation occurs so that, at 1 h after administration, 5-74% of the 125I activity remains associated with the enzyme, depending on the tissue. A small amount of the labeled enzyme is found in washed cells of thymus, lung, spleen, liver and brain.This publication has 3 references indexed in Scilit:
- Protective effect of superoxide dismutase on erythrocytes of X-irradiated miceBiochemical and Biophysical Research Communications, 1976
- Radioprotective effect of superoxide dismutase on model phospholipid membranesBiochimica et Biophysica Acta (BBA) - Biomembranes, 1976
- Superoxide dismutase: Improved assays and an assay applicable to acrylamide gelsAnalytical Biochemistry, 1971