Effect of Arsonic Acid Derivatives in Stimulating Growth of Chickens

Abstract
The growth of chickens fed diets high in soybean meal and deficient in the unknown dietary factor found in fish meal and in cow manure was improved by the addition to the diet of 0.005% of 3-nitro, 4-hydroxyphenyl arsonic acid. The effect of higher or lower levels was less favorable. This compound did not function as a substitute either for the unknown factor or for methionine. On the contrary, with diets containing raw soybeans the arsonic acid derivative, the unknown factor, and methionine were mutually supplementary. The arsonic acid derivative was effective when fed with 35% or with 70% of commercially heated soybean meal, but less effective than the unknown factor. Other compounds comparable in their activity to 3-nitro, 4-hydroxyphenyl arsonic acid were phenyl arsonic acid and p-hydroxyphenyl arsonic acid. M-nitrophenyl arsonic acid also showed some growth-promoting activity. The following were tested and found inactive in this respect: p-chlorophenyl arsonic acid, sodium arsenate, m-nitrobenzenesulfonic acid, salicylic acid, 3-nitrosalicylic acid, and sodium p-phenolsulfonate.

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