Determination of Alcohols, Phenols, and Carboxylic Acids Using Phosphorus-31 NMR Spectroscopy

1 March 1986

journal article
research article
Published by SAGE Publications in Applied Spectroscopy

Vol. 40 (3) , 348-351
https://doi.org/10.1366/0003702864509268

Abstract

Derivatization of compounds containing -OH groups can be accomplished quantitatively with 1,3,2-dioxaphospholanyl chloride. The chemical shifts of phosphorus in the derivatives clearly differentiate alcohols from phenols and carboxylic acids. Quantitation is obtained by use of ³¹P FT-NMR spectroscopy in the presence of 2,2,6,6-tetrameth-ylpiperidinyloxy free radical to shorten relaxation times. Compounds with phosphorus chemical shifts differing by as little as 0.1 ppm can be separately determined.

Keywords

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