The synthesis of estragole labelled with deuterium ln single positions of the allylic side chain. In single positions of the allylic side chain
- 1 January 1979
- journal article
- research article
- Published by Wiley in Journal of Labelled Compounds and Radiopharmaceuticals
- Vol. 16 (5) , 745-752
- https://doi.org/10.1002/jlcr.2580160512
Abstract
[γ‐2H2]Estragole was synthesized via vinylation of 4‐ methoxy‐ [methylene‐2H2]‐benzyl chloride; [β‐2H]estragole via reduction of 3‐(p‐anisyl)‐propyne with bis‐3‐methyl‐2‐butylborane (obtained from LiAl2H4, BF3 etherate and 2‐methyl‐2‐butene) [α‐2H]estragole via reduction of the tosylhydrazone of 4‐methoxy‐[formyl‐2H]‐cinnamaldehyde with NaBH3CN.Keywords
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