Itraconazole trough concentrations in antifungal prophylaxis with six different dosing regimens using hydroxypropyl‐β‐cyclodextrin oral solution or coated‐pellet capsules
- 1 December 1999
- Vol. 42 (11-12) , 591-600
- https://doi.org/10.1046/j.1439-0507.1999.00518.x
Abstract
We have previously shown that a trough concentration of at least 500 ng ml−1 itraconazole is necessary for an effective antifungal prophylaxis in neutropenic patients. Since the bioavailability of it...Keywords
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