A New Diazo Method for the Determination of Ascorbic Acid in Blood Plasma
- 1 January 1967
- journal article
- research article
- Published by Taylor & Francis in Scandinavian Journal of Clinical and Laboratory Investigation
- Vol. 20 (2) , 97-103
- https://doi.org/10.3109/00365516709076928
Abstract
A new method for the determination of ascorbic acid in plasma is described. The method is based on a colour reaction not hitherto known between the zinc chloride double salt of diazotized 4-nitroaniline-2,5-dimethoxy-aniline and ascorbic acid. The study includes a comparison with the titrimetric method of Ingals and the photometric method of Schaffert & Kingsley. The method described is easier, quicker and more reliable than the other methods studied and has an error of 1–2 per cent at normal plasma levels.Keywords
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