Urinary Hydroxyproline in the Elderly with Low Leucocyte Ascorbic Acid Levels
- 21 March 1970
- Vol. 1 (5698) , 732-733
- https://doi.org/10.1136/bmj.1.5698.732
Abstract
Fourteen elderly patients aged 58 to 91 with varying leucocyte ascorbic acid levels had urinary hydroxyproline/creatinine ratios measured before, during, and after treatment with ascorbic acid 1 g. daily for six days. The ratio increased during treatment in those patients whose initial ascorbic acid levels were below 15μg./108 white blood cells. It is suggested that collagen metabolism may be impaired in these patients, and that all such patients should receive ascorbic acid supplements.Keywords
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