Intensive Insulin Therapy in Critically Ill Patients
- 16 May 2002
- journal article
- letter
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 346 (20) , 1586-1588
- https://doi.org/10.1056/nejm200205163462016
Abstract
Van den Berghe and colleagues (Nov. 8 issue)1 report that intensive insulin therapy reduces mortality and morbidity among patients admitted to the surgical intensive care unit. Both the authors and Evans,2 in the accompanying editorial, suggest that strict control of glycemia is the principal factor contributing to the improved outcomes reported. However, insulin might have had a role independent of its effect on glycemia.Keywords
This publication has 14 references indexed in Scilit:
- Intensive Insulin Therapy in Critically Ill PatientsNew England Journal of Medicine, 2001
- Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic ShockNew England Journal of Medicine, 2001
- Hemodynamic and Metabolic Therapy in Critically Ill PatientsNew England Journal of Medicine, 2001
- The Ethics of Placebo-Controlled Trials — A Middle GroundNew England Journal of Medicine, 2001
- Withholding Proven Treatment in Clinical ResearchNew England Journal of Medicine, 2001
- Insulin Inhibits Intranuclear Nuclear Factor B and Stimulates I B in Mononuclear Cells in Obese Subjects: Evidence for an Anti-inflammatory Effect?Journal of Clinical Endocrinology & Metabolism, 2001
- Is insulin an antiinflammatory molecule?Nutrition, 2001
- Immunologic Effects of Acute Hyperglycemia in Nondiabetic RatsJournal of Parenteral and Enteral Nutrition, 1997
- Glucose-insulin-potassium solutions enhance recovery after urgent coronary artery bypass graftingThe Journal of Thoracic and Cardiovascular Surgery, 1997
- Effects of an intravenous infusion of a potassium-glucose-insulin solution on the electrocardiographic signs of myocardial infarctionThe American Journal of Cardiology, 1962