A THEORETICAL STUDY OF THE STRUCTURES OF (GLY‐PRO‐LEU)n AND (GLY‐LEU‐PRO)n*
- 12 January 1978
- journal article
- research article
- Published by Wiley in International Journal of Peptide and Protein Research
- Vol. 11 (1) , 73-81
- https://doi.org/10.1111/j.1399-3011.1978.tb02823.x
Abstract
Theoretical conformation studies have been carried out for the polytripeptides (Gly‐Pro‐Leu)n and (Gly‐Leu‐Pro)n and the Fourier transforms of the structures have been calculated. X‐ray powder patterns of these polymers had indicated that both these polymers take up coiled‐coil triple‐helical structures, but in the case of (Gly‐Pro‐Leu)n it was not clear whether the triple helix is formed by three parallel polypeptide chains or by a single chain folding back on itself (Scatturin et al 1975). Our studies show that both the polytripeptides can take up stereochemically satisfactory triple‐helical structures with three parallel chains. There is also very good agreement between the calculated intensity distribution and that of the observed X‐ray pattern, in each case.Keywords
This publication has 17 references indexed in Scilit:
- CONFORMATIONAL STUDIES ON SEQUENTIAL POLYPEPTIDES. PART VI. STRUCTURAL INVESTIGATIONS ON (Pro-Leu-Gly)10, (Pro-Leu-Gly)n AND (Leu-Pro-Gly)nInternational Journal of Peptide and Protein Research, 2009
- STEREOCHEMICAL RESTRICTIONS ON THE OCCURRENCE OF AMINO ACID RESIDUES IN THE COLLAGEN STRUCTUREInternational Journal of Peptide and Protein Research, 1977
- Primary StructurePublished by Springer Nature ,1976
- Some Stereochemical Implications of the Molecular Conformation of CollagenIsrael Journal of Chemistry, 1974
- Analysis of the primary structure of collagen for the origins of molecular packingJournal of Molecular Biology, 1973
- STUDY OF HYDROGEN BONDS IN AMINO ACIDS AND PEPTIDES*International Journal of Protein Research, 1971
- Studies on the conformation of amino acids XII. Energy calculations on prolyl residueBiochimica et Biophysica Acta (BBA) - Protein Structure, 1970
- Helix-Coil Transition in Collagen. Evidence for a Single-Stranded Triple Helix*Biochemistry, 1967
- Conformational Transitions of Poly-L-proline and Poly-(L-prolyl-glycyl-L-proline)Published by Elsevier ,1967
- Synthesis of Poly-(l-prolyl-l-leucyl-glycyl). An Attempted Synthesis of Model CollagenBulletin of the Chemical Society of Japan, 1958