Block copolymers of amino acids. II. Physicochemical data on copolymers containing L‐alanine or L‐phenylalanine
- 1 September 1977
- journal article
- research article
- Published by Wiley in Biopolymers
- Vol. 16 (9) , 2029-2051
- https://doi.org/10.1002/bip.1977.360160915
Abstract
The water‐soluble block copolymers, whose syntheses were described in the preceding paper, were subjected to ultracentrifugation, viscosity, optical rotatory dispersion circular dichroism, fluorescence, proton magnetic resonance, and infrared measurements. Discrepancies between Mn and Mw, and line broadening in the proton magnetic resonance spectra (attributed to the formation of rigid structures), support the conclusion (drawn in the preceding paper) that the block copolymers are aggregated in aqueous solution. It is shown that similar block copolymers reported in the literature are also aggregated.This publication has 25 references indexed in Scilit:
- Helix-Coil Stability Constants for the Naturally Occurring Amino in Water. VII Phenylalanine Parameters from Random Poly(hydroxypropylglutamine-co-L-L-phenylalanine)Macromolecules, 1973
- Helix-Coil Stability Constants for the Naturally Occurring Amino Acids in Water. VI. Leucine Parameters from Random Poly(hydroxypropylglutamine-co-L-leucine) and Poly(hydroxybutylglutamine-co-L-leucine)Macromolecules, 1972
- Nuclear Magnetic Resonance Study of Hydrophobic Bonding in (D,L-Lysine)m-(L-Alanine)n-(D,L-Lysine)mMacromolecules, 1972
- Block sequential polypeptides of L‐alanine and glycine with D, L‐glutamic acidBiopolymers, 1971
- Laser Raman Spectroscopy of Polypeptides. I. Water-Soluble Block Copoymers of L-Alanine and D,L-LysineMacromolecules, 1971
- Nuclear magnetic resonance studies of side-chain interactions in polyamino acids with aromatic groups. Comparison to conformational energy calculationsBiochemistry, 1971
- Effect of side-chain hydrophobic bonding on the stability of homopolyamino acid ?-helices: Conformational studies of poly-L-leucine in waterBiopolymers, 1970
- Helix-coil transition of poly-l-phenylalanine studied by nuclear magnetic resonanceJournal of Molecular Biology, 1968
- Solution properties of synthetic polypeptides. II. Sedimentation and viscosity of poly‐γ‐benzyl‐L‐glutamate in dimethylformamideBiopolymers, 1966
- A Conformation Examination of Poly-L-alanine and Poly-D,L-alanine in Aqueous SolutionJournal of the American Chemical Society, 1963