IMMUNOHISTOCHEMICAL LOCALIZATION OF HISTAMINASE (DIAMINE OXIDASE) IN DECIDUAL CELLS OF HUMAN PLACENTA

  • 1 January 1978
    • journal article
    • research article
    • Vol. 38  (6) , 703-706
Abstract
An immunohistochemical technique was developed for localization of histaminase (diamine oxidase) in human placenta. The procedure utilized antibody to highly purified human placental enzyme prepared in rabbits. Histaminase apparently was present in cytoplasm of decidual cells of the maternal placenta; staining was specific and was removed by preabsorption of the antisera with purified antigen. The enzyme was not a fetal product in this tissue. The presence of histaminase in some human tumors and in normal tissues like kidney and intestine apparently was the result of the expression of a mature and not a fetal genome.