Excretion of Ca45 into the Gastrointestinal Tract of Young and Mature Rats

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Abstract
The excretory rate of various segments of the intestinal tract of young and mature rats has been studied by the use of radioactive calcium. Appreciable quantities of Ca45 were found in the tissue and contents of the tract as early as 15 minutes after intramuscular injection. The data indicate that all segments of the tract participate in the excretion of calcium with the small intestine playing a major role in this capacity, which is contrary to the view that the large intestine predominates in this function. Fecal recovery indicated that extensive excretion of the isotope had occurred by way of the alimentary tract. After a two-week period, 15.22 and 41.55% of the dose were recovered in the feces of the young and mature rats, respectively.