Tumor volume measurements of acoustic neuromas with three-dimensional constructive interference in steady state and conventional spin-echo MR imaging

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Abstract
The purpose was to compare three‐dimensional (3D) constructive interference in steady state (CISS) and conventional spin‐echo (SE) MR imaging in tumor volume measurements of acoustic neuromas. Twenty‐two patients with acoustic neuromas were examined using high‐resolution 3D‐CISS and SE imaging at a 1.5‐T system. Tumor volume determined by SE imaging with the ellipsoid formula was overestimated by 692 mm3(35%) on average as compared with that at 3D‐CISS with the voxel‐count method (the reference standard). Intra‐ and interobserver variations in SE imaging were poor as compared with 3D‐CISS imaging. However, tumor volume results with SE imaging showed a high correlation with those using 3D‐CISS imaging (P < .0001). On the basis of diameters shown on SE images, the tumor volume could be assessed using the following equation (P < .0001): (Tumor volume) = −26.407 + 0.387 × (maximum diameter along the pyramid) ×(maximum diameter perpendicular to the pyramid) × (maximum height). J. Magn. Reson. Imaging 2000;12:826–832.