Abstract
1. Thyroidectomy in rats produces a diminution both of nitrogen and of calcium output.2. After parathyroidectomy in rats there seems to be an increase of calcium in the urine, and less is retained in the body, but nitrogenous metabolism shows no definite change.3. Thyroid feeding produces a decrease in body‐weight and a diminution of nitrogen and gaseous metabolism in all the animals, whether normal, thyroidectomised, or parathyroidectomised.4. Castration is attended in male rats by diminution of CO2 output.

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