Karyotypic stability and speciation in Hawaiian Drosophila.

Abstract
Speciation among a selected and closely knit group of 22 endemic Hawaiian species of Drosphila has resulted in pronounced morphological divergence. No change in metaphase karyotype was detected and the giant polytene chromosomes reveal only moderate reorganization by inversions. In 4 separate instances, 2 or more species were formed without detectable change in the banding sequences of any of the giant chromosomes. Given the existence of such homosequential species having large morphological differences, it is possible for speciation and evolution to be based entirely on mutational changes occurring at the sub-microscopic level. Chromosome changes, when they occur inter-specifically, appear to be incidental accompaniments of speciation.

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