CHRONIC DEMYELINATING PERIPHERAL NEUROPATHY ASSOCIATED WITH MULTIFOCAL CENTRAL NERVOUS SYSTEM DEMYELINATION

1 February 1987

journal article
case report
Published by Oxford University Press (OUP) in Brain

Vol. 110 (1) , 53-76
https://doi.org/10.1093/brain/110.1.53

Abstract

A series of 6 cases is described in which a chronic demyelinating neuropathy was associated with a relapsing multifocal CNS disorder, the clinical features of which resembled multiple sclerosis. Multifocal CNS lesions were demonstrated by CT and MR imaging and the presence of CNS demyelination was indicated by prolonged central conduction times. These cases are discussed in relation to the occurrence of combined peripheral and central demyelination in chronic relapsing experimental allergic encephalomyelitis and neuritis.

Keywords

CENTRAL NERVOUS SYSTEM
PERIPHERAL DEMYELINATING NEUROPATHY
DEMYELINATION
MAGNETIC RESONANCE IMAGING
CENTRAL NERVOUS SYSTEM DYSFUNCTION
EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS
MULTIPLE SCLEROSIS
NEURITIS
SIGNS AND SYMPTOMS
CENTRAL NERVOUS SYSTEM LESION

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