The Effects of Irradiation on the Haematopoietic Tissues of Anaesthetized Mice

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Abstract
The effects of irradiation on the haematopoietic tissues of anaesthetized mice have bee measured using the balance between damage and recovery during the 10-day period following the administration of various doses of whole-body- X-irradiation. The cellularity of the femoral bone marrow, the weight of the spleen and the number of (endogenous) spleen colonies are elevated in animals anaesthetized using Avertin during exposure to doses of whole-body X-irradiation in the range between 400 and 850 rad, with a dose reduction factor of 1.2–1.4

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