Chemical and Biochemical Studies with Dithioate DNA
- 1 January 1991
- journal article
- plenary lectures
- Published by Taylor & Francis in Nucleosides and Nucleotides
- Vol. 10 (1-3) , 47-59
- https://doi.org/10.1080/07328319108046435
Abstract
Dithioate DNA was synthesized and used for various biochemical studies. Results from these studies indicate that dithioate DNA is a potent inhibitor of HIV Reverse Transcriptase, activates endogenous RNase H in Hela cell nuclear extracts, and is a useful probe for studying protein-DNA interactions.Keywords
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