Hyperthermia induced pathophysiology of the central nervous system
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- 1 January 2003
- journal article
- review article
- Published by Taylor & Francis in International Journal of Hyperthermia
- Vol. 19 (3) , 325-354
- https://doi.org/10.1080/0265673021000054621
Abstract
This review is focused on the pathophysiology of the central nervous system (CNS) associated with mild-to-moderate hyperthermia (body temperature > 37°C but 40°C but <42°C). This effect depends on the age of the animals and their prior thermal experiences. Taken together, heat stress induced hyperthermia, once believed to be non-toxic in the mammalian CNS, do produce specific alterations in the CNS that may have long-term behavioural, physiological and neuropathological consequences. The probable mechanism(s) underlying hyperthermia induced brain pathology is discussed.Keywords
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