Inhibition of rabies virus infection by a soluble membrane fraction from the rat central nervous system
- 1 March 1988
- journal article
- research article
- Published by Springer Nature in Archiv für die gesamte Virusforschung
- Vol. 98 (1-2) , 73-86
- https://doi.org/10.1007/bf01321007
Abstract
Summary This paper describes the inhibitory effect of a normal rat brain solubilized membrane preparation (RBSM-liposomes) on rabies virus infection. Rabies virus was incubated with RBSM-liposomes or their separated components (proteins, phospholipids, gangliosides) before infection of CER or neuroblastoma cells. In addition, both RBSM-liposomes and target cells were treated with enzymes prior to the infection step. All these experimental procedures showed that the active components were mainly lipids.Keywords
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