A Clinical Technique for Prevention of Spasm and Preservation of Endothelium in Saphenous Vein Grafts

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Abstract
• Spasm and endothelial injury during harvesting of saphenous vein grafts can be prevented by a protocol that involves perivenous infiltration with 37 °C papaverine hydrochloride solution prior to skin incision, initial distention of the vein with the same warm papaverine solution, storage of the distended vein graft in a cold papaverine solution, and maintenance of the vein in the distended state throughout the operative procedure. This technique preserves endothelial integrity In human reversed saphenous vein grafts. (Arch Surg 1984;119:1212-1214)

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