INFLAMMATORY MARKERS AND THE RISK OF ALZHEIMER DISEASE: THE FRAMINGHAM STUDY

Publisher Website
Google Scholar
Abstract
The authors have avoided the necessity of taking serial CSF samples by using a surrogate marker of TNF-alpha, its production by peripheral blood mononuclear cells. This technique may have traversed the fact that large molecules such as TNF-alpha have difficulty in crossing the blood–brain barrier, although in the case of TNF-alpha there may be a modest degree of crossing due to the existence of active transport mechanisms.2

This publication has 0 references indexed in Scilit: