Intramolecular photoarylation of enamino-ketones: simple synthesis of hexahydroapoerysopine dimethyl ether
- 1 January 1977
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 18,p. 644-645
- https://doi.org/10.1039/c39770000644
Abstract
A novel synthesis of hexahydroapoerysopine dimethyl ether (11), by photolytic intramolecular arylation of the 6′-iodo- and 7-bromo-derivatives of 1,2,3,3a,4,5-hexahydro-N-(3,4-dimethoxyphenethyl)indol-6-one (6) and (8) to 2,3-dihydroapoerysopin-1(3aH)-one (9), followed by reduction with LiAlH4 to cis-2,3,3a,12c-tetrahydroapoerysopine (10) and then hydrogenation, is reported.This publication has 0 references indexed in Scilit: