Is IL-1 a good therapeutic target in the treatment of arthritis?

This publication has 121 references indexed in Scilit:

• IL-33, an Interleukin-1-like Cytokine that Signals via the IL-1 Receptor-Related Protein ST2 and Induces T Helper Type 2-Associated Cytokines
  Immunity, 2005
• Preliminary results of safety and efficacy of the interleukin 1 receptor antagonist anakinra in patients with severe lupus arthritis
  Annals of the Rheumatic Diseases, 2005
• Patient- versus physician-reported outcomes in rheumatoid arthritis patients treated with recombinant interleukin-1 receptor antagonist (anakinra) therapy
  Rheumatology, 2004
• Anticytokine treatment of established type II collagen–induced arthritis in DBA/1 mice: A comparative study using anti‐TNFα, anti–IL‐1α/β, and IL‐1Ra
  Arthritis & Rheumatism, 1996
• Role of interleukin‐1, tumor necrosis factor α, and interleukin‐6 in cartilage proteoglycan metabolism and destruction effect of in situ blocking in murine antigen‐ and zymosan‐induced arthritis
  Arthritis & Rheumatism, 1995
• The type II ‘decoy’ receptor: A novel regulatory pathway for interleukin 1
  Immunology Today, 1994
• LOCALIZATION OF INTERLEUKIN-1α, TYPE 1 INTERLEUKIN-1 RECEPTOR AND INTERLEUKIN-1 RECEPTOR ANTAGONIST IN THE SYNOVIAL MEMBRANE AND CARTILAGE/PANNUS JUNCTION IN RHEUMATOID ARTHRITIS
  Rheumatology, 1992
• Arthritis induced by interleukin-1 is dependent on the site and frequency of intraarticular injection
  Clinical Immunology and Immunopathology, 1990
• Biological properties of recombinant human monocyte-derived interleukin 1 receptor antagonist.
  Journal of Clinical Investigation, 1990
• Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts.
  The Journal of Experimental Medicine, 1985