Paraldehyde Toxicity During Treatment of Status Epilepticus
- 1 May 1982
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Pediatrics & Adolescent Medicine
- Vol. 136 (5) , 414-415
- https://doi.org/10.1001/archpedi.1982.03970410032006
Abstract
• A 2-month-old girl survived a lethal serum level of paraldehyde after being given the drug intravenously (IV) for status epilepticus. On the basis of known pharmacokinetic data in man, a slow IV infusion, over a period of five minutes, of 200 mg/kg of paraldehyde followed by a drip of 20 mg/kg/hr should result in safe, rapid control of status epilepticus when first-line anticonvulsant drugs have failed. The paraldehyde should be diluted to a 10% solution with 5% dextrose water. (Am J Dis Child 1982;136:414-415)This publication has 7 references indexed in Scilit:
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