Megaloblastic Anemia

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Abstract
MEGALOBLASTIC anemia is the hematologic result of any of a variety of etiologic factors causing improper nucleoprotein synthesis.1 Of these factors by far the most common are deficiencies of vitamin B12 or folate or both. Such deficiencies account for at least 95 per cent of all patients with megaloblastic anemia. The remainder — less than 5 per cent — probably include a number who have inadequate utilization of vitamin B12 or of folic acid, or both, as seemed to be true, at least in part, in a patient with liver disease who had a slight hematologic response to . . .