Synthesis of Optically Active 4-Benzyloxymethyl- and 4-(4-Methoxyphenoxy)methylbuten-2-olides via Lipase-Mediated Resolution

Abstract
A new preparation of optically active 4-benzyloxymethyl- and 4-(4-methoxyphenoxy)methylbuten-2-olides has been developed by employing lipase-mediated resolution and palladium-mediated carbomethoxylation as key steps.

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