DNA-BAR: distinguisher selection for DNA barcoding
Open Access
- 16 June 2005
- journal article
- Published by Oxford University Press (OUP) in Bioinformatics
- Vol. 21 (16) , 3424-3426
- https://doi.org/10.1093/bioinformatics/bti547
Abstract
DNA-BAR is a software package for selecting DNA probes (henceforth referred to as distinguishers) that can be used in genomic-based identification of microorganisms. Given the genomic sequences of the microorganisms, DNA-BAR finds a near-minimum number of distinguishers yielding a distinct hybridization pattern for each microorganism. Selected distinguishers satisfy user specified bounds on length, melting temperature and GC content, as well as redundancy and cross-hybridization constraints.Keywords
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