Simultaneous Development of Platelet Factor 4 Activity and Release of 14C-Serotonin
- 1 January 1971
- journal article
- schattauer gmbh
- Published by Georg Thieme Verlag KG in Thrombosis and Haemostasis
- Vol. 25 (01) , 041-046
- https://doi.org/10.1055/s-0038-1654278
Abstract
Development of platelet factor 4 activity induced under various conditions by ADP, epinephrine, or connective tissue correlated well with release of 14C-serotonin measured simultaneously. In many ways connective tissue behaved differently from ADP and epinephrine, e.g., it caused PF-4 activity and 140-serotonin release in unstirred platelet-rich plasma and was effective in platelet-rich plasma from a thrombasthenic patient whereas ADP and epinephrine were not. * Work partially supported by U.S. Public Health Service Grant No. HE-12859, National Heart and Lung Institute. Contribution No. 201 from the Blood Research Laboratories, American National Red Cross. ** Please send reprint requests to Dr. Zucker. Present affiliation, Department of Pathology.Keywords
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