The effects of histamine H2-receptor antagonists on PHA induced lymphocyte proliferation
- 1 October 1984
- journal article
- research article
- Published by Springer Nature in Inflammation Research
- Vol. 15 (3-4) , 242-248
- https://doi.org/10.1007/bf01972356
Abstract
Histamine H2-receptor antagonists must be used with caution to define the pharmacology of histamine effects on lymphocyte mitogenesis induced by PHA because they can enhance and/or suppress in their own right, because these effects are similar to those of histamine itself because mitogenic doses of PHA can release significant amounts of histamine from supposedly pure mononuclear cell preparations.Keywords
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