C′3 Synthesis in the Human Fetus and Lack of Transplacental Passage
- 8 November 1968
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 162 (3854) , 672-673
- https://doi.org/10.1126/science.162.3854.672
Abstract
Allotypic differences in the third component of complement between mothers and their newborns provided evidence for synthesis of this complement component by the fetus. There was no indication that this protein traversed the placenta. The known low level of C'3 in the neonate was confirmed, and the maternal concentration was found to be significantly elevated.Keywords
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