The role and prevalence of Gardnerella vaginalis in anaerobic vaginosis
- 1 March 1990
- journal article
- research article
- Published by Springer Nature in Infection
- Vol. 18 (2) , 83-85
- https://doi.org/10.1007/bf01641420
Abstract
310 cases of anaerobic vaginosis and 80 asymptomatic females were studied for the detection of various organisms from their genital specimens. The main complaint of the symptomatic cases was vaginal discharge.Neisseria gonorrhoeae, Candida albicans, Trichomonas vaginalis. Bacteroides species, anaerobic cocci andGardnerella vaginalis were detected. The frequency of detection of all exceptC. albicans was less in pregnant than non-pregnant women. However, the prevalence of anaerobes andG. vaginalis was significantly lower in both the symptomatic and asymptomatic pregnant than the non-pregnant women.G. vaginalis showed mutualism with anaerobic bacteria and was not isolated as a pure culture in any of the cases. It appears thatG. vaginalis, like anaerobes, has variable prevalence rates and is under the influence of local physiological and hormonal factors. This organism does not appear to have a primary pathogenic role, but assumes a secondary role in association with non-sporing anaerobes in the pathogenesis of anaerobic vaginosis. 310 Fälle von anaerober Vaginose und 80 asymptomatische Frauen wurden auf die Keimzusammensetzung ihres Vaginalsekrets untersucht. Fluor war die Hauptbeschwerde der symptomatischen Fälle. Nachgewiesen wurdenNeisseria gonorrhoeae, Candida albicans, Trichomonas vaginalis, Bacteroides sp., anaerobe Kokken undGardnerella vaginalis. Mit Ausnahme vonC. albicans fanden sich alle Isolate bei Schwangeren seltener als bei nicht schwangeren Frauen. Signifikant seltener wurden bei Schwangeren mit oder ohne Symptome Anaerobier undG. vaginalis gefunden.G. vaginalis und Anaerobier traten assoziiert auf, in Reinkultur wurdeG. vaginalis in keinem Fall isoliert. Wie bei Anaerobiern läßt sich beiC. albicans eine wechselnde Prävalenz beobachten, für die lokale physiologische und hormonale Faktoren eine Rolle spielen. Dieser Keim scheint als primärer Krankheitserreger keine Rolle zu spielen, hat jedoch in Assoziation mit nicht sporenbildenden Anaerobiern eine Bedeutung in der Pathogenese der anaeroben Vaginose.This publication has 17 references indexed in Scilit:
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