Viral hepatitis and hepatocellular carcinoma.

  • 1 September 1994
    • journal article
    • review article
    • Vol. 23  (3) , 567-79
Abstract
Hepatocellular carcinoma (HCC) is one of the more common internal malignancies worldwide and is responsible for over 1 million deaths annually. The causative relationship between chronic hepatitis B and HCC is now beyond doubt, and it is likely that the attributable risk of HCC due to hepatitis C virus (HCV) infection is similar to or greater than that for hepatitis B in some countries. The prospects for preventing HCC with the use of a vaccine against HBV appear excellent. Until a vaccine against HCV becomes available, prevention of HCV-related HCC is predominantly dependent on a reduction in transfusion-associated disease.

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