Elimination of Escherichia Coli K88 Adhesion Determinant by Antibody in Porcine Gut and Mammary Secretions Following Oral Immunization
- 1 January 1978
- book chapter
- Published by Springer Nature
- Vol. 107, 133-142
- https://doi.org/10.1007/978-1-4684-3369-2_16
Abstract
Antibody mediated inhibition of bacterial adhesion is one of the prevalent themes in current investigations of protective secretory immune mechanisms in the host-pathogen relationship. The phenomenon of bacterial adhesion is of considerable biological significance (12). In the gastrointestinal tract bacteria may benefit from their adhesion ability in at least two ways: by successful anchorage, thereby resisting the peristaltic fluxes which might otherwise sweep them away, and also by gaining a favorable habitat with a rich source of nutrients. With enteropathogenic E. coli (EEC) this feature creates an additional advantage over the host by allowing for a ready transport of enterotoxin into susceptible regions of the gut, with the consequent interference with biochemical processes across the membrane.Keywords
This publication has 18 references indexed in Scilit:
- BACTERIAL ADHERENCE IN ORAL MICROBIAL ECOLOGYAnnual Review of Microbiology, 1975
- Intestinal defence in the young pig--a review of the secretory antibody systems and their possible role in oral immunisationPublished by Wiley ,1973
- Escherichia coli antigens as dietary additives for oral immunisation of pigs: trials with pig creep feedsPublished by Wiley ,1973
- Protection against Enteric Disease caused by Escherichia coli–a Model for Vaccination with a Virulence Determinant?Nature, 1973
- Observations On The Pathogenic Properties Of The K88, Hly And Ent Plasmids Of Escherichia Coli With Particular Reference To Porcine DiarrhoeaJournal of Medical Microbiology, 1971
- Escherichia coli Infection: Reproduction of the Disease in Naturally-reared PigletsResearch in Veterinary Science, 1963