Treatment of Idiopathic Neutropenia in the Elderly with Recombinant Human Granulocyte Colony-Stimulating Factor
- 1 January 1991
- journal article
- case report
- Published by S. Karger AG in Acta Haematologica
- Vol. 85 (3) , 146-152
- https://doi.org/10.1159/000204878
Abstract
We administered recombinant human granulocyte colony-stimulating factor (rhG-CSF) intravenously for 2 weeks to 2 elderly patients with severe neutropenia. The absolute neutrophil count (ANC) recovered promptly after the initiation of rhG-CSF therapy and reached a peak ( > 10 × 109/l) on the 13th day. The ANC fell rapidly after rhG-CSF was discontinued, but it remained within the normal range after therapy. There were no side effects during the entire course of treatment. Therefore, rhG-CSF seems to be a most beneficial treatment in elderly patients with severe neutropenia.Keywords
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