The ‘Bulging Factor’, a Fungistatic Antibiotic Produced by a Streptomyces Strain, with Evidence of an Active Water-excreting Mechanism in Fungi
Open Access
- 1 December 1957
- journal article
- research article
- Published by Microbiology Society in Microbiology
- Vol. 17 (3) , 596-601
- https://doi.org/10.1099/00221287-17-3-596
Abstract
SUMMARY: The ‘bulging factor’, a new antibiotic with a chemical nature related to streptothricin, is produced by a Streptomyces strain and was isolated as reineckate and picrate. A study on its mode of action resulted in the development of a plate technique for assaying bulging factor activity. Evidence is presented in support of a theory about the existence of an active water-excreting mechanism in fungi susceptible to the bulging factor.Keywords
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