Resection of Colorectal Liver Metastases: Current Perspectives
Open Access
- 1 January 2006
- journal article
- research article
- Published by SAGE Publications in Cancer Control
- Vol. 13 (1) , 32-41
- https://doi.org/10.1177/107327480601300105
Abstract
Metastases to the liver is the leading cause of death in patients with colorectal cancer. The authors review the data on diagnosis and management of this clinical problem, and they discuss management options that can be considered. Complete surgical resection of metastases from colorectal cancer that are localized to the liver results in 5-year survival rates ranging from 26% to 40%. By adding modalities such as targeted systemic therapy and other “local” treatments for liver metastases, further gains in survival are anticipated.Keywords
This publication has 115 references indexed in Scilit:
- OncoSurge: A Strategy for Improving Resectability With Curative Intent in Metastatic Colorectal CancerJournal of Clinical Oncology, 2005
- Neoadjuvant Chemotherapy Before Liver Resection for Patients With Unresectable Liver Metastases From Colorectal CarcinomaJournal of Clinical Oncology, 2005
- Tumor Progression While on ChemotherapyAnnals of Surgery, 2004
- Surgical strategies for colorectal liver metastasesSurgical Oncology, 2004
- A Randomized Controlled Trial of Fluorouracil Plus Leucovorin, Irinotecan, and Oxaliplatin Combinations in Patients With Previously Untreated Metastatic Colorectal CancerJournal of Clinical Oncology, 2004
- Five-Year Survival Following Hepatic Resection After Neoadjuvant Therapy for Nonresectable Colorectal [Liver] MetastasesAnnals of Surgical Oncology, 2001
- Resection of Nonresectable Liver Metastases from Colorectal Cancer After Neoadjuvant ChemotherapyAnnals of Surgery, 1996
- Resection of colorectal liver metastasesWorld Journal of Surgery, 1995
- Factors influencing the natural history of colorectal liver metastasesThe Lancet, 1994
- Repeat liver resection for recurrent colorectal metastasesBritish Journal of Surgery, 1993