7-(2-Aminomethylphenylacetamido)-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid.

1 January 1976

journal article
research article
Published by Japan Antibiotics Research Association in The Journal of Antibiotics

Vol. 29 (11) , 1226-1229
https://doi.org/10.7164/antibiotics.29.1226

Abstract

The synthesis of 7-(2-aminomethylphenylacetamido)-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid (BL-S786) is described and the antimicrobial activities are compared with cefazolin and cefamandole. The compound exhibits broad antimicrobial spectrum, produces high i.m. blood levels in mice and demonstrates a high degree of therapeutic efficacy in experimental bacterial infections in rodents.