Template-independent synthesis of guanosine tetra- and pentaphosphates on ribosomes
- 3 October 1983
- journal article
- Published by Wiley in FEBS Letters
- Vol. 162 (1) , 39-42
- https://doi.org/10.1016/0014-5793(83)81044-8
Abstract
It is shown that Escherichia coli ribosomes carrying poly(Lys)-tRNA can form (p)ppGpp in the presence of stringent factor in the absence of the poly(A) template. Template-independent synthesis of (p)ppGpp is suppressed by tetracycline and partially decreases if deacylated tRNA is omitted.Keywords
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